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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

JPH2 Antibody

CATALOG NUMBER: 57-048

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This JPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 614-643 amino acids from the C-terminal region of human JPH2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
74 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
JPH2
Additional Names:
Junctophilin-2, JP-2, Junctophilin type 2, JPH2, JP2
Protein Accession Number:
Q9BR39
Protein Gi Number:
27805486
Ncbi Gene Id Number:
57158
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Junctional complexes between the plasma membrane andendoplasmic/sarcoplasmic reticulum are a common feature of allexcitable cell types and mediate cross talk between cell surfaceand intracellular ion channels. The protein encoded by this gene isa component of junctional complexes and is composed of a C-terminalhydrophobic segment spanning the endoplasmic/sarcoplasmic reticulummembrane and a remaining cytoplasmic domain that shows specificaffinity for the plasma membrane. This gene is a member of thejunctophilin gene family. Alternative splicing has been observed atthis locus and two variants encoding distinct isoforms aredescribed.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Woo, J.S., et al. Biochem. J. 427(1):125-134(2010)
Background Reference 3:
Yamazaki, D., et al. Pharmacol. Ther. 121(3):265-272(2009)
Background Reference 4:
Landstrom, A.P., et al. J. Mol. Cell. Cardiol. 42(6):1026-1035(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-048

List Size:
400 ul

List Price:

$495.00

Datasheet
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