Junctophilin 3 Antibody

CATALOG NUMBER: 61-445

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Human
Immunogen:
This Junctophilin 3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-578 amino acids from the Central region of human Junctophilin 3.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
81 kDa
Purification:
This antibody is purified through a protein G column, followed by dialysis against PBS.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Jph3
Additional Names:
Junctophilin-3, JP-3, Junctophilin type 3, Jph3, Jp3
Protein Accession Number:
Q9ET77
Ncbi Gene Id Number:
57340
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilin 3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane.
Background Reference 1:
Kakizawa,S., EMBO J. 26 (7), 1924-1933 (2007)
Background Reference 2:
Moriguchi,S., Proc. Natl. Acad. Sci. U.S.A. 103 (28), 10811-10816 (2006)
Background Reference 3:
Nishi,M., Brain Res. Mol. Brain Res. 118 (1-2), 102-110 (2003)
Background Reference 4:
Nishi,M., Biochem. Biophys. Res. Commun. 292 (2), 318-324 (2002)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-445

List Size:
400 ul

List Price:

$495.00

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