Kallikrein 5 Antibody

CATALOG NUMBER: 62-246

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This Kallikrein 5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-174 amino acids from the Central region of human Kallikrein 5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
32 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KLK5
Additional Names:
Kallikrein-5, 3421-, Kallikrein-like protein 2, KLK-L2, Stratum corneum tryptic enzyme, KLK5, SCTE
Protein Accession Number:
Q9Y337
Protein Gi Number:
296434569
Ncbi Gene Id Number:
25818
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 expression is up-regulated by estrogens and progestins. The protein is secreted and may be involved in desquamation in the epidermis.
Background Reference 1:
Planque, C., et al., Biochem. Biophys. Res. Commun. 329(4):1260-1266 (2005). Michael, I.P., et al., J. Biol. Chem. 280(15):14628-14635 (2005). Ishida-Yamamoto, A., et al., J. Invest. Dermatol. 124(2):360-366 (2005). Brattsand, M., et al., J. Invest. Dermatol. 124(1):198-203 (2005). Caubet, C., et al., J. Invest. Dermatol. 122(5):1235-1244 (2004).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-246

List Size:
400 ul

List Price:

$495.00

Shipping Info
Customize your order
Custom Antibody Services

New & Featured Products

CATALOG NUMBER: PM-7369-HRP

CATALOG NUMBER: PM-7369-biotin

CATALOG NUMBER: PM-7369