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Western blot analysis of KAT5 in human brain tissue lysate with KAT5 antibody at 1 μg/mL.
Immunohistochemistry of KAT5 in rat brain tissue with KAT5 antibody at 2.5 μg/ml.
Immunofluorescence of KAT5 in rat brain tissue with KAT5 antibody at 20 μg/ml.
Western blot analysis of KAT5 in human brain tissue lysate with KAT5 antibody at 1 μg/mL.
Trial Size

KAT5 Antibody

CATALOG NUMBER: 7339

Clonality:
Polyclonal
Tested Applications:
ELISA, IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
KAT5 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human KAT5.
The immunogen is located within the last 50 amino acids of KAT5.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IF, IHC-P, WB
Application Note:
KAT5 antibody can be used for detection of KAT5 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Specificity:
Multiple isoforms of KAT5 are known to exist.
Positive Control 1:
Cat. No. 1303 - Human Brain Tissue Lysate
Predicted Molecular Weight:
Predicted: 51, 54, 56, 60 kDa
Observed: 53 kDa
Purification:
KAT5 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
KAT5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
KAT5 antibody can be stored at 4°C, stable for up to one year. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KAT5
Additional Names:
KAT5 Antibody: TIP, ESA1, PLIP, TIP60, cPLA2, HTATIP, ZC2HC5, HTATIP1, Histone acetyltransferase KAT5, 60 kDa Tat-interactive protein, Tip60
Protein Accession Number:
NP_874369
Protein Gi Number:
36287069
Ncbi Gene Id Number:
10524
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
KAT5 Antibody: KAT5 belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and non-histone proteins. KAT5 has been shown to play a role in DNA repair and apoptosis and is thought to play an important role in signal transduction and autophagy.
Background Reference 1:
Kamine J, Elangovan B, Subramanian T, et al. Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator. Virology 1996; 216:357-66.
Background Reference 2:
Kimura A and Horikoshi M. Tip60 acetylates six lysines of a specific class of core histones in vitro. Genes Cells 1998; 3:789-800.
Background Reference 3:
Ikura T, Ogryzko VV, Grigoriev M, et al. Involvement of the TIP70 histone acetylase complex in DNA repair and apoptosis. Cell 2000; 102:463-73.
Background Reference 4:
Lin SY, Li TY, Liu Q, et al. GSK3-TIP60-ILK1 signaling pathway links growth factor deprivation to autophagy. Science 2012; 336:477-81.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

7339

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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