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Western blot analysis in 293 cell line lysates (35ug/lane).
Western blot analysis in 293 cell line lysates (35ug/lane).

KATNA1 Antibody

CATALOG NUMBER: 60-126

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This KATNA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-85 amino acids from the N-terminal region of human KATNA1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
56 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KATNA1
Additional Names:
Katanin p60 ATPase-containing subunit A1 {ECO:0000255, HAMAP-Rule:MF_03023}, Katanin p60 subunit A1 {ECO:0000255, HAMAP-Rule:MF_03023}, 3643 {ECO:0000255, HAMAP-Rule:MF_03023}, p60 katanin {ECO:0000255, HAMAP-Rule:MF_03023}, KATNA1 {ECO:0000255, HAMAP-Rule:MF_03023}
Protein Accession Number:
O75449
Ncbi Gene Id Number:
11104
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Microtubules, polymers of alpha and beta tubulin subunits,form the mitotic spindle of a dividing cell and help to organizemembranous organelles during interphase. Katanin is a heterodimerthat consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDaaccessory protein (p80 subunit B 1). The p60 subunit acts to severand disassemble microtubules, while the p80 subunit targets theenzyme to the centrosome. This gene encodes the p80 subunit. Thisprotein is a member of the AAA family of ATPases. [provided byRefSeq].
Background Reference 1:
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 2:
Iwaya, N., et al. J. Biol. Chem. 285(22):16822-16829(2010)
Background Reference 3:
Sudo, H., et al. Hum. Mol. Genet. 17(16):2524-2540(2008)
Background Reference 4:
Mungall, A.J., et al. Nature 425(6960):805-811(2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-126

List Size:
400 ul

List Price:

$495.00

Datasheet
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