KATNB1 Antibody

CATALOG NUMBER: 58-590

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This KATNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-359 amino acids from the Central region of human KATNB1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
72 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KATNB1
Additional Names:
Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000255, HAMAP-Rule:MF_03022}, Katanin p80 subunit B1 {ECO:0000255, HAMAP-Rule:MF_03022}, p80 katanin {ECO:0000255, HAMAP-Rule:MF_03022}, KATNB1 {ECO:0000255, HAMAP-Rule:MF_03022}
Protein Accession Number:
Q9BVA0
Protein Gi Number:
60390213
Ncbi Gene Id Number:
10300
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Microtubules, polymers of alpha and beta tubulin subunits,form the mitotic spindle of a dividing cell and help to organizemembranous organelles during interphase. Katanin is a heterodimerthat consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDaaccessory protein (p80 subunit B 1). The p60 subunit acts to severand disassemble microtubules, while the p80 subunit targets theenzyme to the centrosome. Katanin is a member of the AAA family ofATPases.
Background Reference 1:
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 2:
Cummings, C.M., et al. J. Biol. Chem. 284(17):11663-11675(2009)
Background Reference 3:
Sudo, H., et al. Hum. Mol. Genet. 17(16):2524-2540(2008)
Background Reference 4:
Olsen, J.V., et al. Cell 127(3):635-648(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-590

List Size:
400 ul

List Price:

$495.00

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