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Antibody used in IHC on Human kidney.
Antibody used in WB on Human Jurkat 0.65 ug/ml.
Antibody used in IHC on Human kidney.

KCNAB3 Antibody

CATALOG NUMBER: 28-248

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNAB3.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
KCNAB3 antibody can be used for detection of KCNAB3 by ELISA at 1:12500. KCNAB3 antibody can be used for detection of KCNAB3 by western blot at 0.65 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
44 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store KCNAB3 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
KCNAB3
Additional Names:
KCNAB3, AKR6A9, KCNA3B, KCNA3.1B, KV-BETA-3
Protein Accession Number:
NP_004723
Protein Gi Number:
27436971
Ncbi Gene Id Number:
9196
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member and the KCNA5 gene product assemble into a heteromultimeric A-type channel that inactivates completely and is significantly faster than other A-type Kv channels.
Background Reference 1:
Leicher, T., et al., (1998) J. Biol. Chem. 273 (52), 35095-35101.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-248

List Size:
100 ul

List Price:

$473.00

Datasheet
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