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Western blot analysis in Jurkat cell line lysates (35ug/lane).
Western blot analysis in Jurkat cell line lysates (35ug/lane).

KCNAB3 Antibody

CATALOG NUMBER: 59-918

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This KCNAB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-204 amino acids from the Central region of human KCNAB3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
44 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KCNAB3
Additional Names:
Voltage-gated potassium channel subunit beta-3, K(+) channel subunit beta-3, Kv-beta-3, KCNAB3, KCNA3B
Protein Accession Number:
O43448
Ncbi Gene Id Number:
9196
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Voltage-gated potassium (Kv) channels represent the mostcomplex class of voltage-gated ion channels from both functionaland structural standpoints. Their diverse functions includeregulating neurotransmitter release, heart rate, insulin secretion,neuronal excitability, epithelial electrolyte transport, smoothmuscle contraction, and cell volume. Four sequence-relatedpotassium channel genes - shaker, shaw, shab, and shal - have beenidentified in Drosophila, and each has been shown to have humanhomolog(s). This gene encodes a member of the potassium channel,voltage-gated, shaker-related subfamily. This member is one of thebeta subunits, which are auxiliary proteins associating withfunctional Kv-alpha subunits. This member and the KCNA5 geneproduct assemble into a heteromultimeric A-type channel thatinactivates completely and is significantly faster than otherA-type Kv channels.
Background Reference 1:
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Background Reference 2:
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Background Reference 3:
Leicher, T., et al. J. Biol. Chem. 273(52):35095-35101(1998)
Background Reference 4:
McCormack, K., et al. FEBS Lett. 370 (1-2), 32-36 (1995) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-918

List Size:
400 ul

List Price:

$495.00

Datasheet
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