KCNB2 Antibody

CATALOG NUMBER: 60-604

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Bovine
Immunogen:
This KCNB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids from the N-terminal region of human KCNB2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
103 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KCNB2
Additional Names:
Potassium voltage-gated channel subfamily B member 2, Voltage-gated potassium channel subunit Kv22, KCNB2
Protein Accession Number:
Q92953
Protein Gi Number:
24418855
Ncbi Gene Id Number:
9312
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Voltage-gated potassium (Kv) channels represent the mostcomplex class of voltage-gated ion channels from both functionaland structural standpoints. Their diverse functions includeregulating neurotransmitter release, heart rate, insulin secretion,neuronal excitability, epithelial electrolyte transport, smoothmuscle contraction, and cell volume. Four sequence-relatedpotassium channel genes - shaker, shaw, shab, and shal - have beenidentified in Drosophila, and each has been shown to have humanhomolog(s). This gene encodes a member of the potassium channel,voltage-gated, shab-related subfamily. This member is a delayedrectifier potassium channel. The gene is expressed ingastrointestinal smooth muscle cells.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Cirulli, E.T., et al. Eur. J. Hum. Genet. 18(7):815-820(2010)
Background Reference 3:
Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)
Background Reference 4:
Nyholt, D.R., et al. Hum. Mol. Genet. 17(21):3318-3331(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-604

List Size:
400 ul

List Price:

$495.00

Shipping Info
Customize your order
Custom Antibody Services

New & Featured Products

CATALOG NUMBER: PM-7369-HRP

CATALOG NUMBER: PM-7369-biotin

CATALOG NUMBER: PM-7369