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Western blot analysis in HepG2 cell line lysates (35ug/lane).
KCNC1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in HepG2 cell line lysates (35ug/lane).

KCNC1 Antibody

CATALOG NUMBER: 57-805

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This KCNC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 479-508 amino acids from the C-terminal region of human KCNC1.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
58 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KCNC1
Additional Names:
Potassium voltage-gated channel subfamily C member 1, NGK2, Voltage-gated potassium channel subunit Kv31, Voltage-gated potassium channel subunit Kv4, KCNC1
Protein Accession Number:
P48547
Protein Gi Number:
1352085
Ncbi Gene Id Number:
3746
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The Shaker gene family of Drosophila encodes components ofvoltage-gated potassium channels and is comprised of foursubfamilies. Based on sequence similarity, this gene is similar toone of these subfamilies, namely the Shaw subfamily. The proteinencoded by this gene belongs to the delayed rectifier class ofchannel proteins and is an integral membrane protein that mediatesthe voltage-dependent potassium ion permeability of excitablemembranes. Multiple transcript variants encoding different isoformshave been inferred for this gene based on orthologous loci.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 3:
Wang, Z., et al. J. Gen. Physiol. 133(4):361-374(2009)
Background Reference 4:
Gutman, G.A., et al. Pharmacol. Rev. 57(4):473-508(2005)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-805

List Size:
400 ul

List Price:

$495.00

Datasheet
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