KCNC4 Antibody

CATALOG NUMBER: 58-639

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This KCNC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-546 amino acids from the C-terminal region of human KCNC4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
70 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KCNC4
Additional Names:
Potassium voltage-gated channel subfamily C member 4, KSHIIIC, Voltage-gated potassium channel subunit Kv34, KCNC4
Protein Accession Number:
Q03721
Protein Gi Number:
66774206
Ncbi Gene Id Number:
3749
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The Shaker gene family of Drosophila encodes components ofvoltage-gated potassium channels and is comprised of foursubfamilies. Based on sequence similarity, this gene is similar tothe Shaw subfamily. The protein encoded by this gene belongs to thedelayed rectifier class of channel proteins and is an integralmembrane protein that mediates the voltage-dependent potassium ionpermeability of excitable membranes. It generates atypicalvoltage-dependent transient current that may be important forneuronal excitability. Multiple transcript variants have been foundfor this gene.
Background Reference 1:
Mosing, M.A., et al. Twin Res Hum Genet 13(4):398-403(2010)
Background Reference 2:
Menendez, S.T., et al. J. Pathol. 221(4):402-410(2010)
Background Reference 3:
Leblanc, N. Cardiovasc. Res. 86(3):351-352(2010)
Background Reference 4:
Miguel-Velado, E., et al. Cardiovasc. Res. 86(3):383-391(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-639

List Size:
400 ul

List Price:

$495.00

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