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Western blot analysis in K562 cell line lysates (35ug/lane).
KCND2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in K562 cell line lysates (35ug/lane).

KCND2 Antibody

CATALOG NUMBER: 58-024

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Rat
Immunogen:
This KCND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-151 amino acids from the N-terminal region of human KCND2.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
71 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KCND2
Additional Names:
Potassium voltage-gated channel subfamily D member 2, Voltage-gated potassium channel subunit Kv42, KCND2, KIAA1044
Protein Accession Number:
Q9NZV8
Protein Gi Number:
38258257
Ncbi Gene Id Number:
3751
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Voltage-gated potassium (Kv) channels represent the mostcomplex class of voltage-gated ion channels from both functionaland structural standpoints. Their diverse functions includeregulating neurotransmitter release, heart rate, insulin secretion,neuronal excitability, epithelial electrolyte transport, smoothmuscle contraction, and cell volume. Four sequence-relatedpotassium channel genes - shaker, shaw, shab, and shal - have beenidentified in Drosophila, and each has been shown to have humanhomolog(s). This gene encodes a member of the potassium channel,voltage-gated, shal-related subfamily, members of which formvoltage-activated A-type potassium ion channels and are prominentin the repolarization phase of the action potential. This membermediates a rapidly inactivating, A-type outward potassium currentwhich is not under the control of the N terminus as it is in Shakerchannels.
Background Reference 1:
Foeger, N.C., et al. J. Biol. Chem. 285(43):33413-33422(2010)
Background Reference 2:
Levy, D.I., et al. J. Physiol. (Lond.) 588 (PT 14), 2657-2668 (2010) :
Background Reference 3:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 4:
Aronica, E., et al. Neurobiol. Dis. 36(1):81-95(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-024

List Size:
400 ul

List Price:

$495.00

Datasheet
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