KCNE4 Antibody

CATALOG NUMBER: 59-910

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This KCNE4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the Central region of human KCNE4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
24 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KCNE4
Additional Names:
Potassium voltage-gated channel subfamily E member 4, MinK-related peptide 3, Minimum potassium ion channel-related peptide 3, Potassium channel subunit beta MiRP3, KCNE4
Protein Accession Number:
Q8WWG9
Protein Gi Number:
311033433
Ncbi Gene Id Number:
23704
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Voltage-gated potassium (Kv) channels represent the mostcomplex class of voltage-gated ion channels from both functionaland structural standpoints. Their diverse functions includeregulating neurotransmitter release, heart rate, insulin secretion,neuronal excitability, epithelial electrolyte transport, smoothmuscle contraction, and cell volume. This gene encodes a member ofthe potassium channel, voltage-gated, isk-related subfamily. Thismember is a type I membrane protein, and a beta subunit thatassembles with a potassium channel alpha-subunit to modulate thegating kinetics and enhance stability of the multimeric complex.This gene is prominently expressed in the embryo and in adultuterus.
Background Reference 1:
Levy, D.I., et al. J. Physiol. (Lond.) 588 (PT 14), 2657-2668 (2010) :
Background Reference 2:
Sole, L., et al. J. Cell. Sci. 122 (PT 20), 3738-3748 (2009) :
Background Reference 3:
Trevino, L.R., et al. Nat. Genet. 41(9):1001-1005(2009)
Background Reference 4:
Manderfield, L.J., et al. J. Physiol. (Lond.) 587 (PT 2), 303-314 (2009) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-910

List Size:
400 ul

List Price:

$495.00

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