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Antibody used in WB on Human Jurkat 1.25 ug/ml.
Antibody used in WB on Human Jurkat 1.25 ug/ml.

KCNN1 Antibody

CATALOG NUMBER: 28-240

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNN1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
KCNN1 antibody can be used for detection of KCNN1 by ELISA at 1:312500. KCNN1 antibody can be used for detection of KCNN1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
60 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store KCNN1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
KCNN1
Additional Names:
KCNN1, SK1, hSK1, SKCA1, KCa2.1
Protein Accession Number:
NP_002239
Protein Gi Number:
25777643
Ncbi Gene Id Number:
3780
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. KCNN1 is a member of the KCNN family of potassium channels.
Background Reference 1:
Arnold, S.J., et al., (2003) Neuroreport 14 (2), 191-195.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-240

List Size:
100 ul

List Price:

$473.00

Datasheet
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