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Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.

KCNQ2 Antibody

CATALOG NUMBER: 28-293

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNQ2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
KCNQ2 antibody can be used for detection of KCNQ2 by ELISA at 1:12500. KCNQ2 antibody can be used for detection of KCNQ2 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
93 kDa, 94 kDa, 96 kDa, 93 kDa, 44 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store KCNQ2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
KCNQ2
Additional Names:
KCNQ2, EBN, BFNC, EBN1, ENB1, BFNS1, EIEE7, HNSPC, KV7.2, KCNA11, KVEBN1
Protein Accession Number:
NP_004509
Protein Gi Number:
26051260
Ncbi Gene Id Number:
3785
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by KCNQ2 and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).
Background Reference 1:
Tang, B., et al., (2004) J. Neurol. Sci. 221 (1-2), 31-34.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-293

List Size:
100 ul

List Price:

$519.00

Datasheet
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