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KCNQ3 Antibody

CATALOG NUMBER: 42-090

Clonality:
Polyclonal
Tested Applications:
ELISA
Host Species:
Goat
Conjugate:
Unconjugated
Specifications
Host Species:
Goat
Homology:
Expected Species Reactivity based on sequence homology: Human, Mouse, Rat, Pig
Immunogen:
The immunogen for this antibody is: C-SDSVWTPSNKPI
Conjugate:
Unconjugated
Tested Applications:
ELISA
Application Note:
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Preliminary experiments gave an approx. 23kDa band in Human Brain (Cerebral Cortex, Amygdala, Hippocampus) lysates after 0.3ug/ml antibody staining. Please note that currently we can not find an explanation in the literature for the band we observe given the calculated size of 96.7kDa according to NP_004510.1. The 23kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Storage Conditions:
Aliquot and store at -20°C. Minimize freezing and thawing.
Ncbi Official Symbol:
KCNQ3
Additional Names:
KCNQ3, potassium voltage-gated channel, KQT-like subfamily, member 3, BFNC2, EBN2, KV7.3, potassium channel, voltage-gated, subfamily Q, member 3, potassium voltage-gated channel KQT-like protein 3
Protein Accession Number:
NP_004510.1
Protein Gi Number:
4758630
Ncbi Gene Id Number:
3786
Background Reference 1:
Ekberg J, Schuetz F, Boase NA, Conroy SJ, Manning J, Kumar S, Poronnik P, Adams DJ. Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2. J Biol Chem. 2007 Apr 20;282(16):12135-42.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

42-090

List Size:
0.1 mg

List Price:

$391.00

Datasheet
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