KHDRBS3 Antibody

CATALOG NUMBER: 60-293

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This KHDRBS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-47 amino acids from the N-terminal region of human KHDRBS3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
39 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KHDRBS3
Additional Names:
KH domain-containing, RNA-binding, signal transduction-associated protein 3, RNA-binding protein T-Star, Sam68-like mammalian protein 2, SLM-2, Sam68-like phosphotyrosine protein, KHDRBS3, SALP, SLM2
Protein Accession Number:
O75525
Ncbi Gene Id Number:
10656
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression.
Background Reference 1:
Xin, X., et al. Genome Res. 19(7):1262-1269(2009)
Background Reference 2:
Lu, Y., et al. PLoS ONE(7), E6159 (2009) :
Background Reference 3:
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Background Reference 4:
Schymick, J.C., et al. Lancet Neurol 6(4):322-328(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-293

List Size:
400 ul

List Price:

$495.00

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