KIR2DL3 Recombinant Protein

CATALOG NUMBER: 96-492

Tested Applications:
WB
Specifications
Source Species:
HEK293 cells
Species:
Human
Source Species:
HEK293 cells
Recombinant Protein Sequence:
His 22 - His 245
Fusion Tag:
C-Fc Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
51.2 kDa
Purity:
>95% as determined by SDS-PAGE.
Physical State:
Lyophilized
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
KIR2DL3
Additional Names:
KIR2DL3, CD158B2, KIRCL23, NKAT2, KIR-023GB, NKAT2a, NKAT2b, NKAT-2, CD158 B2, GL183, KIR-023GB, KIR-K7b, KIR-K7c, KIRCL23, NKAT, p58
Protein Accession Number:
NP_056952
Ncbi Gene Id Number:
3804
Background:
Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3) is also known as CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2 and KIR2DL3, which is a single-pass type I membrane protein and belongs to the immunoglobulin superfamily.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). KIR2DL3 can inhibit the activity of NK cells thus preventing cell lysis.
Background Reference 1:
Colonna M., et al., 1995 Science 268:405-408.
Background Reference 2:
Doehring C., et al., 1996, Immunogenetics 44:227-230.
Background Reference 3:
Maenaka K., et al., 1999, Structure 7:391-398.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-492

List Size:
0.1 mg

List Price:

$430.00

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