KIT Antibody

CATALOG NUMBER: 60-079

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 937-966 amino acids from the C-terminal region of human KIT.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
110 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KIT
Additional Names:
Mast/stem cell growth factor receptor Kit, SCFR, Piebald trait protein, PBT, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, CD117, KIT, SCFR
Protein Accession Number:
P10721
Protein Gi Number:
125472
Ncbi Gene Id Number:
3815
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes the human homolog of the proto-oncogenec-kit. C-kit was first identified as the cellular homolog of thefeline sarcoma viral oncogene v-kit. This protein is a type 3transmembrane receptor for MGF (mast cell growth factor, also knownas stem cell factor). Mutations in this gene are associated withgastrointestinal stromal tumors, mast cell disease, acutemyelogenous lukemia, and piebaldism. Multiple transcript variantsencoding different isoforms have been found for this gene.
Background Reference 1:
Molderings, G.J., et al. Immunogenetics 62 (11-12), 721-727 (2010) :
Background Reference 2:
Cheng, M., et al. Circ. Res. 107(9):1083-1093(2010)
Background Reference 3:
Chi, P., et al. Nature 467(7317):849-853(2010)
Background Reference 4:
Rossi, S., et al. Am. J. Surg. Pathol. 34(10):1480-1491(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-079

List Size:
400 ul

List Price:

$495.00

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