KLF4 Antibody

CATALOG NUMBER: 28-337

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KLF4.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
KLF4 antibody can be used for detection of KLF4 by ELISA at 1:312500. KLF4 antibody can be used for detection of KLF4 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Tranfected 293T Cell Lysate
Predicted Molecular Weight:
50 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store KLF4 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
KLF4
Additional Names:
KLF4, EZF, GKLF
Protein Accession Number:
NP_004226
Protein Gi Number:
194248077
Ncbi Gene Id Number:
9314
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.
Background Reference 1:
Yoon, H.S., (2005) Oncogene 24 (25), 4017-4025.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-337

List Size:
100 ul

List Price:

$473.00

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