KLK15 Antibody

CATALOG NUMBER: 58-018

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This KLK15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-106 amino acids from the Central region of human KLK15.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
28 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KLK15
Additional Names:
Kallikrein-15, 3421-, ACO protease, KLK15
Protein Accession Number:
Q9H2R5
Protein Gi Number:
18202940
Ncbi Gene Id Number:
55554
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Kallikreins are a subgroup of serine proteases havingdiverse physiological functions. Growing evidence suggests thatmany kallikreins are implicated in carcinogenesis and some havepotential as novel cancer and other disease biomarkers. This geneis one of the fifteen kallikrein subfamily members located in acluster on chromosome 19. In prostate cancer, this gene hasincreased expression, which indicates its possible use as adiagnostic or prognostic marker for prostate cancer. The genecontains multiple polyadenylation sites and alternative splicingresults in multiple transcript variants encoding distinct isoforms.
Background Reference 1:
Rabien, A., et al. Int. J. Cancer 127(10):2386-2394(2010)
Background Reference 2:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 3:
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Background Reference 4:
Gallagher, D.J., et al. Clin. Cancer Res. 16(10):2819-2832(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-018

List Size:
400 ul

List Price:

$495.00

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