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KLRG1 Antibody [2F1]

CATALOG NUMBER: 77-088

Clonality:
Monoclonal
Tested Applications:
Flow, Functional Assays, IP
Host Species:
Hamster
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Hamster
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Tested Applications:
Flow, Functional Assays, IP
Specificity:
The 2F1 monoclonal antibody is specific for the mouse Killer cell Lectin-like Receptor G1 (KLRG1), a homodimer consisting of two N-glycosylated subunits of 30-38 kDa, also known as MAFA (Mast cell Function-associated Antigen).
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Golden Syrian Hamster IgG
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Klrg1
Additional Names:
MAFA, 2F1-Ag, MAFA-L, Klrg1
Ncbi Gene Id Number:
50928
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 2F1 monoclonal antibody is specific for the mouse Killer cell Lectin-like Receptor G1 (KLRG1), a homodimer consisting of two N-glycosylated subunits of 30-38 kDa, also known as MAFA (Mast cell Function-associated Antigen). The antigen contains a cytoplasmic motif similar to ITIM (the immunoreceptor tyrosine-based inhibitory motif). KLRG1 is a receptor for cadherin, a family of transmembrane glycoproteins that mediate cell adhesion, and a common marker of T cell senescence. The receptor is believed to play an important role in the innate and adaptive immune system through the regulation of leukocytes. It is expressed on lymphokine-activated killer (LAK) cells, adherent LAK (A-LAK) cells, a sub-set of natural killer (NK) cells, T cells. In NK cells, it inhibits cytokine production and cytotoxicity activity.The receptor expression was not detected on the mouse peritoneal mast cells, or bone marrow mast cells.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

77-088

List Size:
0.1 mg

List Price:

$217.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

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