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KMO Antibody

CATALOG NUMBER: 39-869

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to an internal region between amino acids 200-299.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
ELISA, Western (immuno) blotting, Immunostaining (in testing)
Purification:
Affinity Purified
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Concentration:
batch dependent
Ncbi Official Symbol:
Kmo
Additional Names:
317G22.1, KMO_HUMAN, Kynurenine 3 hydroxylase, Kynurenine 3 monooxygenase (kynurenine 3 hydroxylase), Kynurenine 3 monooxygenase, Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase, RP1-317G22.1, AI046660,
Protein Accession Number:
EDL13209
Protein Gi Number:
81879610
Ncbi Gene Id Number:
98256
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Kynurenine 3-monooxygenase (KMO) catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). The enzyme is required for synthesis of quinolinic acid. Quinolinic acid ia a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development.
Background Reference 1:
Eniko Vamosa, Arpad Pardutza, Peter Klivenyia, Jozsef Toldib and Laszlo Vecsei, The role of kynurenines in disorders of the central nervous system: Possibilities for neuroprotection. 2009 Journal of the Neurological Sciences Article in Press, Corrected Proof available on line

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

39-869

List Size:
0.1 mg

List Price:

$626.00

Datasheet
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