KRT3 Antibody

CATALOG NUMBER: 58-702

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This KRT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-441 amino acids from the Central region of human KRT3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
64 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KRT3
Additional Names:
Keratin, type II cytoskeletal 3, 65 kDa cytokeratin, Cytokeratin-3, CK-3, Keratin-3, K3, Type-II keratin Kb3, KRT3
Protein Accession Number:
P12035
Protein Gi Number:
313104225
Ncbi Gene Id Number:
3850
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of thekeratin gene family. The type II cytokeratins consist of basic orneutral proteins which are arranged in pairs of heterotypic keratinchains coexpressed during differentiation of simple and stratifiedepithelial tissues. This type II cytokeratin is specificallyexpressed in the corneal epithelium with family member KRT12 andmutations in these genes have been associated with Meesmann'sCorneal Dystrophy. The type II cytokeratins are clustered in aregion of chromosome 12q12-q13.
Background Reference 1:
Szaflik, J.P., et al. Mol. Vis. 14, 1713-1718 (2008) :
Background Reference 2:
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)
Background Reference 3:
Chen, Y.T., et al. Cornea 24(8):928-932(2005)
Background Reference 4:
Rogers, M.A., et al. J. Invest. Dermatol. 124(3):536-544(2005)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-702

List Size:
400 ul

List Price:

$495.00

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