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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

KRT6A Antibody

CATALOG NUMBER: 58-847

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This KRT6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the N-terminal region of human KRT6A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KRT6A
Additional Names:
Keratin, type II cytoskeletal 6A, Cytokeratin-6A, CK-6A, Cytokeratin-6D, CK-6D, Keratin-6A, K6A, Type-II keratin Kb6, Hom s 5, KRT6A, K6A, KRT6D
Protein Accession Number:
P02538
Protein Gi Number:
1346344
Ncbi Gene Id Number:
3853
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of thekeratin gene family. The type II cytokeratins consist of basic orneutral proteins which are arranged in pairs of heterotypic keratinchains coexpressed during differentiation of simple and stratifiedepithelial tissues. As many as six of this type II cytokeratin(KRT6) have been identified; the multiplicity of the genes isattributed to successive gene duplication events. The genes areexpressed with family members KRT16 and/or KRT17 in the filiformpapillae of the tongue, the stratified epithelial lining of oralmucosa and esophagus, the outer root sheath of hair follicles, andthe glandular epithelia. This KRT6 gene in particular encodes themost abundant isoform. Mutations in these genes have beenassociated with pachyonychia congenita. The type II cytokeratinsare clustered in a region of chromosome 12q12-q13. [provided byRefSeq].
Background Reference 1:
Dereure, O. Ann Dermatol Venereol 137(5):423-424(2010)
Background Reference 2:
Trost, A., et al. Mech. Ageing Dev. 131(5):346-353(2010)
Background Reference 3:
Yang, L., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27(1):66-68(2010)
Background Reference 4:
Millar, E.K., et al. J. Clin. Oncol. 27(28):4701-4708(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-847

List Size:
400 ul

List Price:

$495.00

Datasheet
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