KRT72 Antibody

CATALOG NUMBER: 60-728

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This KRT72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-342 amino acids from the Central region of human KRT72.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
56 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KRT72
Additional Names:
Keratin, type II cytoskeletal 72, Cytokeratin-72, CK-72, Keratin-72, K72, Type II inner root sheath-specific keratin-K6irs2, Type-II keratin Kb35, KRT72, K6IRS2, KB35, KRT6, KRT6IRS2
Protein Accession Number:
Q14CN4
Protein Gi Number:
166218813
Ncbi Gene Id Number:
140807
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Keratins are intermediate filament proteins responsiblefor the structural integrity of epithelial cells. The type IIkeratins consist of basic or neutral proteins which are arranged inpairs of heterotypic keratin chains coexpressed duringdifferentiation of simple and stratified epithelial tissues. Thisgene encodes a type II keratin that is specifically expressed inthe inner root sheath of hair follicles. The type II keratins areclustered in a region of chromosome 12q12-q13. Multiple transcriptvariants encoding different isoforms have been found for this gene.
Background Reference 1:
Bertheau, P., et al. PLoS Med.(3), E90 (2007) :
Background Reference 2:
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)
Background Reference 3:
Langbein, L., et al. J. Invest. Dermatol. 120(4):512-522(2003)
Background Reference 4:
Porter, R.M., et al. Br. J. Dermatol. 145(4):558-568(2001)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-728

List Size:
400 ul

List Price:

$495.00

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