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Western blot analysis in A375 cell line lysates (35ug/lane).
Western blot analysis in A375 cell line lysates (35ug/lane).

KRT75 Antibody

CATALOG NUMBER: 58-736

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This KRT75 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-92 amino acids from the N-terminal region of human KRT75.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KRT75
Additional Names:
Keratin, type II cytoskeletal 75, Cytokeratin-75, CK-75, Keratin-6 hair follicle, hK6hf, Keratin-75, K75, Type II keratin-K6hf, Type-II keratin Kb18, KRT75, K6HF, KB18
Protein Accession Number:
O95678
Ncbi Gene Id Number:
9119
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the type II keratin familyclustered on the long arm of chromosome 12. Type I and type IIkeratins heteropolymerize to form intermediate-sized filaments inthe cytoplasm of epithelial cells. This gene is expressed in thecompanion layer, upper germinative matrix region of the hairfollicle, and medulla of the hair shaft. The encoded protein playsan essential role in hair and nail formation. Variations in thisgene have been associated with the hair disorderspseudofolliculitis barbae (PFB) and loose anagen hair syndrome(LAHS).
Background Reference 1:
Sperling, L.C., et al. J. Cutan. Pathol. 37(2):243-248(2010)
Background Reference 2:
Liu, Z.B., et al. Tumori 95(1):53-62(2009)
Background Reference 3:
Nofech-Mozes, S., et al. Int. J. Surg. Pathol. 16(4):399-406(2008)
Background Reference 4:
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-736

List Size:
400 ul

List Price:

$495.00

Datasheet
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