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Western blot analysis in U251 cell line lysates (35ug/lane).
Western blot analysis in U251 cell line lysates (35ug/lane).

KRT86 Antibody

CATALOG NUMBER: 60-876

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This KRT86 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-327 amino acids from the Central region of human KRT86.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
54 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
KRT86
Additional Names:
Keratin, type II cuticular Hb6, Hair keratin K211, Keratin-86, K86, Type II hair keratin Hb6, Type-II keratin Kb26, KRT86, KRTHB6
Protein Accession Number:
O43790
Ncbi Gene Id Number:
3892
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of thekeratin gene family. As a type II hair keratin, it is a basicprotein which heterodimerizes with type I keratins to form hair andnails. The type II hair keratins are clustered in a region ofchromosome 12q13 and are grouped into two distinct subfamiliesbased on structure similarity. One subfamily, consisting of KRTHB1,KRTHB3, and KRTHB6, is highly related. The other less-relatedsubfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratinsare expressed in the hair follicle; this hair keratin, as well asKRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutationsin this gene and KRTHB1 have been observed in patients with a raredominant hair disease, monilethrix.
Background Reference 1:
ZHANG, S.D., et al. EurDermatol 19(5):508-509(2009)
Background Reference 2:
Feng, A.P., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 25(2):141-144(2008)
Background Reference 3:
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Background Reference 4:
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-876

List Size:
400 ul

List Price:

$495.00

Datasheet
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