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Antibody used in WB on Human Brain at 0.2-1 ug/ml.
Antibody used in WB on Human Brain at 0.2-1 ug/ml.

L3MBTL Antibody

CATALOG NUMBER: 25-388

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human L3MBTL.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
L3MBTL antibody can be used for detection of L3MBTL by ELISA at 1:1562500. L3MBTL antibody can be used for detection of L3MBTL by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Predicted Molecular Weight:
86 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store L3MBTL antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
L3MBTL1
Additional Names:
L3MBTL, DKFZp586P1522, FLJ41181, H-L(3)MBT, KIAA0681, L3MBTL1, dJ138B7.3, L3MBTL, ZC2HC3
Protein Accession Number:
NP_056293
Protein Gi Number:
117938328
Ncbi Gene Id Number:
26013
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
L3MBTL is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells.This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
Background Reference 1:
Min, J., (2007) Nat. Struct. Mol. Biol. 14 (12), 1229-1230.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-388

List Size:
100 ul

List Price:

$519.00

Datasheet
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