LAG-3 Antibody [17B4]

CATALOG NUMBER: 36-107

Clonality:
Monoclonal
Tested Applications:
Functional Assays, ICC, IHC, IP, WB
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Immunogen:
Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.
Conjugate:
Unconjugated
Tested Applications:
Functional Assays, ICC, IHC, IP, WB
Application Note:
Immunohistochemistry: (EM). Immunoprecipitation: (1-2ug/ml) . Western Blot: (1-5ug/ml) . Optimal conditions must be determined individually for each application.
Specificity:
Recognizes human LAG-3.
Purification:
>95% (SDS-PAGE)
Clonality:
Monoclonal
Isotype:
IgG1
physical-state:
Liquid
Buffer:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Concentration:
1 mg/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C.
Ncbi Official Symbol:
LAG3
Additional Names:
Lymphocyte Activation Gene-3; FDC Protein; CD223
Protein Accession Number:
251757512
Protein Gi Number:
P18627
Ncbi Gene Id Number:
3902
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-107

List Size:
100 ug

List Price:

$495.00

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