LAIR1 Antibody

CATALOG NUMBER: 57-270

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This LAIR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human LAIR1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
31 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LAIR1
Additional Names:
Leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, hLAIR1, CD305, LAIR1, CD305
Protein Accession Number:
Q6GTX8
Protein Gi Number:
74736490
Ncbi Gene Id Number:
3903
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is an inhibitory receptorfound on peripheral mononuclear cells, including NK cells, T cells,and B cells. Inhibitory receptors regulate the immune response toprevent lysis of cells recognized as self. The gene is a member ofboth the immunoglobulin superfamily and the leukocyte-associatedinhibitory receptor family. The gene maps to a region of 19q13.4called the leukocyte receptor cluster, which contains at least 29genes encoding leukocyte-expressed receptors of the immunoglobulinsuperfamily.
Background Reference 1:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 2:
Brondijk, T.H., et al. Blood 115(7):1364-1373(2010)
Background Reference 3:
Tang, X., et al. J. Immunol. 182(9):5446-5452(2009)
Background Reference 4:
Lebbink, R.J., et al. Matrix Biol. 28(4):202-210(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-270

List Size:
400 ul

List Price:

$495.00

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