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Western blot analysis in mouse kidney tissue lysates (15ug/lane).This demonstrates the detected LCLT1 protein (arrow).
LCLT1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in mouse kidney tissue lysates (15ug/lane).This demonstrates the detected LCLT1 protein (arrow).

LCLT1 Antibody

CATALOG NUMBER: 62-021

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This LCLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the C-terminal region of human LCLT1.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
49 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LCLAT1
Additional Names:
Lysocardiolipin acyltransferase 1, 231-, 1-acylglycerol-3-phosphate O-acyltransferase 8, 1-AGP acyltransferase 8, 1-AGPAT 8, Acyl-CoA:lysocardiolipin acyltransferase 1, LCLAT1, AGPAT8, ALCAT1, LYCAT
Protein Accession Number:
Q6UWP7
Protein Gi Number:
74749398
Ncbi Gene Id Number:
253558
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages.
Background Reference 1:
Zhao, Y., et al. J. Lipid Res. 50(5):945-956(2009)
Background Reference 2:
Wang, C., et al. Blood 110(10):3601-3609(2007)
Background Reference 3:
Agarwal, A.K., et al. Arch. Biochem. Biophys. 449 (1-2), 64-76 (2006)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-021

List Size:
400 ul

List Price:

$495.00

Datasheet
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