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Western blot analysis in Jurkat cell line lysates (35ug/lane).
Western blot analysis in Jurkat cell line lysates (35ug/lane).

LCP1 Antibody

CATALOG NUMBER: 60-157

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This LCP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-335 amino acids from the Central region of human LCP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
70 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LCP1
Additional Names:
Plastin-2, L-plastin, LC64P, Lymphocyte cytosolic protein 1, LCP-1, LCP1, PLS2
Protein Accession Number:
P13796
Protein Gi Number:
308153685
Ncbi Gene Id Number:
3936
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Plastins are a family of actin-binding proteins that areconserved throughout eukaryote evolution and expressed in mosttissues of higher eukaryotes. In humans, two ubiquitous plastinisoforms (L and T) have been identified. Plastin 1 (otherwise knownas Fimbrin) is a third distinct plastin isoform which isspecifically expressed at high levels in the small intestine. The Lisoform is expressed only in hemopoietic cell lineages, while the Tisoform has been found in all other normal cells of solid tissuesthat have replicative potential (fibroblasts, endothelial cells,epithelial cells, melanocytes, etc.). However, L-plastin has beenfound in many types of malignant human cells of non-hemopoieticorigin suggesting that its expression is induced accompanyingtumorigenesis in solid tissues.
Background Reference 1:
Wabnitz, G.H., et al. Eur. J. Immunol. 40(9):2437-2449(2010)
Background Reference 2:
Janji, B., et al. J. Cell. Mol. Med. 14 (6A), 1264-1275 (2010) :
Background Reference 3:
Le Goff, E., et al. Cytoskeleton (Hoboken) 67(5):286-296(2010)
Background Reference 4:
Al Tanoury, Z., et al. PLoS ONE(2), E9210 (2010) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-157

List Size:
400 ul

List Price:

$495.00

Datasheet
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