LDOC1L Antibody

CATALOG NUMBER: 59-990

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This LDOC1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-186 amino acids from the C-terminal region of human LDOC1L.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
26 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LDOC1L
Additional Names:
Protein LDOC1L, Leucine zipper protein down-regulated in cancer cells-like, Mammalian retrotransposon-derived protein 6, LDOC1L, MAR6, MART6
Protein Accession Number:
Q6ICC9
Protein Gi Number:
74762303
Ncbi Gene Id Number:
84247
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
LDOC1 (Leucine zipper protein downregulated in cancer cells) is a 146 amino acid nuclear protein that contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is downregulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kB (NF-kB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. LDOC1L (Leucine zipper protein down-regulated in cancer cells-like), also known as MART6 (Mammalian retrotransposon-derived protein 6), is a 239 amino acid protein that belongs to the LDOC1 family.
Background Reference 1:
Brandt, J., et al. Gene 345(1):101-111(2005)
Background Reference 2:
Brandt, J., et al. Cytogenet. Genome Res. 110 (1-4), 307-317 (2005) :
Background Reference 3:
Collins, J.E., et al. Genome Biol.(10), R84 (2004) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-990

List Size:
400 ul

List Price:

$495.00

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