LETM1 Antibody

CATALOG NUMBER: 59-207

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This LETM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 577-607 amino acids from the C-terminal region of human LETM1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
83 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LETM1
Additional Names:
LETM1 and EF-hand domain-containing protein 1, mitochondrial, Leucine zipper-EF-hand-containing transmembrane protein 1, LETM1
Protein Accession Number:
O95202
Ncbi Gene Id Number:
3954
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein that is localized to the innermitochondrial membrane. The protein functions to maintain themitochondrial tubular shapes and is required for normalmitochondrial morphology and cellular viability. Mutations in thisgene cause Wolf-Hirschhorn syndrome, a complex malformationsyndrome caused by the deletion of parts of the distal short arm ofchromosome 4. Related pseudogenes have been identified onchromosomes 8, 15 and 19.
Background Reference 1:
Jiang, D., et al. Science 326(5949):144-147(2009)
Background Reference 2:
Piao, L., et al. Cell. Signal. 21(5):767-777(2009)
Background Reference 3:
Piao, L., et al. Cancer Res. 69(8):3397-3404(2009)
Background Reference 4:
Tamai, S., et al. J. Cell. Sci. 121 (PT 15), 2588-2600 (2008) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-207

List Size:
400 ul

List Price:

$495.00

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