LGALS3BP Antibody

CATALOG NUMBER: 60-709

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This LGALS3BP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-412 amino acids from the Central region of human LGALS3BP.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
65 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LGALS3BP
Additional Names:
Galectin-3-binding protein, Basement membrane autoantigen p105, Lectin galactoside-binding soluble 3-binding protein, Mac-2-binding protein, MAC2BP, Mac-2 BP, Tumor-associated antigen 90K, LGALS3BP, M2BP
Protein Accession Number:
Q08380
Protein Gi Number:
47115668
Ncbi Gene Id Number:
3959
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The galectins are a family of beta-galactoside-bindingproteins implicated in modulating cell-cell and cell-matrixinteractions. LGALS3BP has been found elevated in the serum ofpatients with cancer and in those infected by the humanimmunodeficiency virus (HIV). It appears to be implicated in immuneresponse associated with natural killer (NK) andlymphokine-activated killer (LAK) cell cytotoxicity. Usingfluorescence in situ hybridization the full length 90K cDNA hasbeen localized to chromosome 17q25. The native protein bindsspecifically to a human macrophage-associated lectin known as Mac-2and also binds galectin 1.
Background Reference 1:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 2:
Srirajaskanthan, R., et al. Mol. Cell Proteomics 9(4):656-666(2010)
Background Reference 3:
Zambelli, D., et al. Int. J. Cancer 126(1):41-52(2010)
Background Reference 4:
Lee, J.H., et al. Pathology 41(3):229-233(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-709

List Size:
400 ul

List Price:

$495.00

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