LILRA2 Antibody

CATALOG NUMBER: 55-193

Clonality:
Polyclonal
Tested Applications:
Flow, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This LILRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-81 amino acids from the Central region of human LILRA2.
Conjugate:
Unconjugated
Tested Applications:
Flow, WB
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
Predicted Molecular Weight:
53 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LILRA2
Additional Names:
Leukocyte immunoglobulin-like receptor subfamily A member 2, CD85 antigen-like family member H, Immunoglobulin-like transcript 1, ILT-1, Leukocyte immunoglobulin-like receptor 7, LIR-7, CD85h, LILRA2, ILT1, LIR7
Protein Accession Number:
Q8N149
Protein Gi Number:
37537906
Ncbi Gene Id Number:
11027
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Leukocyte Ig-like receptors (LIRs) are a family ofimmunoreceptors expressed predominantly on monocytes and B cellsand at lower levels on dendritic cells and natural killer (NK)cells. All LIRs in subfamily B have an inhibitory function (see,e.g., LILRB1, MIM 604811). LIRs in subfamily A, with shortcytoplasmic domains lacking an immunoreceptor tyrosine-basedinhibitory motif (ITIM) and with transmembrane regions containing acharged arginine residue, may initiate stimulatory cascades. Onemember of subfamily A (LILRA3; MIM 604818) lacks a transmembraneregion and is presumed to be a soluble receptor.
Background Reference 1:
Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)
Background Reference 2:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 3:
Jones, D.C., et al. Eur. J. Immunol. 39(11):3195-3206(2009)
Background Reference 4:
Chen, Y., et al. J. Mol. Biol. 386(3):841-853(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-193

List Size:
400 ul

List Price:

$495.00

Shipping Info
Customize your order
Custom Antibody Services

New & Featured Products

CATALOG NUMBER: PM-7369-HRP

CATALOG NUMBER: PM-7369-biotin

CATALOG NUMBER: PM-7369