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Western blot analysis of LINGO1 Antibody in mouse cerebellum tissue lysates (35ug/lane)
Western blot analysis of LINGO1 Antibody in mouse cerebellum tissue lysates (35ug/lane)

LINGO1 Antibody

CATALOG NUMBER: 62-794

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Mouse
Immunogen:
This LINGO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the N-terminal region of human LINGO1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
70 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LINGO1
Additional Names:
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat and immunoglobulin domain-containing protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A, LINGO1, LERN1, LRRN6A
Protein Accession Number:
Q96FE5
Protein Gi Number:
74760819
Ncbi Gene Id Number:
84894
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
LINGO1 is a functional component of the Nogo receptor signaling complex(RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. It is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.
Background Reference 1:
Inoue,H., Proc. Natl. Acad. Sci. U.S.A. 104 (36), 14430-14435 (2007)
Background Reference 2:
Satoh,J., Neuropathol. Appl. Neurobiol. 33 (1), 99-107 (2007)
Background Reference 3:
Mosyak,L., J. Biol. Chem. 281 (47), 36378-36390 (2006)
Background Reference 4:
Mi,S., Nat. Neurosci.(3), 221-228 (2004)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-794

List Size:
400 ul

List Price:

$495.00

Datasheet
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