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E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

LMAN1 Antibody

CATALOG NUMBER: XW-7869

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human
Immunogen:
270-470
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
ERGIC-53 protein antibody can be used for the detection of ERGIC-53 protein by Western Blot.
Predicted Molecular Weight:
57.5 kDa (calculated)
Purification:
Immunoaffinity Purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
LMAN1 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LMAN1
Additional Names:
ERGIC53, F5F8D, Protein ERGIC-53, ER-Golgi intermediate compartment 53 kDa protein, MR60, gp58, FMFD1, MCFD1, ERGIC53, ERGIC-53, ERGIC53 protein, Lectin, mannose-binding 1, Gp58, Intracellular mannose-specific lectin MR60
Protein Accession Number:
NP_005561.1
Protein Gi Number:
5031873
Ncbi Gene Id Number:
3998
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
FUNCTION: Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.

DISEASE: Defects in LMAN1 are a cause of factor V and factor VIII combined deficiency (F5F8D) [MIM:227300]; also known as multiple coagulation factor deficiency I (MCFD1). F5F8D is an autosomal recessive bleeding disorder characterized by coordinate reduction of both clotting proteins. Affected patients present with a moderate bleeding tendency and have factor V and factor VIII levels in the range of 5-30% of normal.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7869

List Size:
0.05 mg

List Price:

$615.00

Out of stock

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