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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

LMBR1 Antibody

CATALOG NUMBER: 59-097

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This LMBR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human LMBR1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
55 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LMBR1
Additional Names:
Limb region 1 protein homolog, Differentiation-related gene 14 protein, LMBR1, C7orf2, DIF14
Protein Accession Number:
Q8WVP7
Protein Gi Number:
74730878
Ncbi Gene Id Number:
64327
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the LMBR1-like membraneprotein family. Another member of this protein family has beenshown to be a lipocalin transmembrane receptor. A highly conserved,cis-acting regulatory module for the sonic hedgehog gene is locatedwithin an intron of this gene. Consequently, disruption of thisgenic region can alter sonic hedgehog expression and affect limbpatterning, but it is not known if this gene functions directly inlimb development. Mutations and chromosomal deletions andrearrangements in this genic region are associated with acheiropodyand preaxial polydactyly, which likely result from altered sonichedgehog expression.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Farooq, M., et al. Eur. J. Hum. Genet. 18(6):733-736(2010)
Background Reference 3:
Rutsch, F., et al. Nat. Genet. 41(2):234-239(2009)
Background Reference 4:
He, F., et al. PLoS ONE(8), E2948 (2008) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-097

List Size:
400 ul

List Price:

$495.00

Datasheet
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