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Western blot analysis in Hela cell line lysates (35ug/lane).
Western blot analysis in Hela cell line lysates (35ug/lane).

LONP1 Antibody

CATALOG NUMBER: 60-602

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This LONP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-418 amino acids from the Central region of human LONP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
106 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LONP1
Additional Names:
Lon protease homolog, mitochondrial {ECO:0000255, HAMAP-Rule:MF_03120}, 3421- {ECO:0000255, HAMAP-Rule:MF_03120}, LONHs, Lon protease-like protein {ECO:0000255, HAMAP-Rule:MF_03120}, LONP {ECO:0000255, HAMAP-Rule:MF_03120}, Mitochondrial ATP-dependent protease Lon {ECO:0000255, HAMAP-Rule:MF_03120}, Serine protease 15 {ECO:0000255, HAMAP-Rule:MF_03120}, LONP1 {ECO:0000255, HAMAP-Rule:MF_03120}, PRSS15
Protein Accession Number:
P36776
Protein Gi Number:
12644239
Ncbi Gene Id Number:
9361
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a mitochondrial matrix protein in theLon family of ATP-dependent proteases. A similar E. coli proteinregulates gene expression by targeting specific regulatory proteinsfor degradation. This protein binds a specific sequence in thelight and heavy chain promoters of the mitochondrial genome whichare involved in regulation of DNA replication and transcription.
Background Reference 1:
Hansen, J., et al. Neurobiology 153(2):474-482(2008)
Background Reference 2:
Chen, S.H., et al. Nucleic Acids Res. 36(4):1273-1287(2008)
Background Reference 3:
Bogenhagen, D.F., et al. J. Biol. Chem. 283(6):3665-3675(2008)
Background Reference 4:
Bayot, A., et al. Biochimie 90(2):260-269(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-602

List Size:
400 ul

List Price:

$495.00

Datasheet
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