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LPAM-1 Antibody [DATK32] (Biotin)

CATALOG NUMBER: 77-136

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
Biotin
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
Biotin
Tested Applications:
Flow
Specificity:
The DATK32 monoclonal antibody specifically reacts with an epitoPEof the Mousealpha4beta7 integrin (LPAM-1).
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Rat IgG2a, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Itga4
Additional Names:
CD49D, Itga4B, Itga4
Ncbi Gene Id Number:
16401
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The DATK32 monoclonal antibody specifically reacts with an epitoPEof the Mousealpha4beta7 integrin (LPAM-1). The two subunits of the LPAM-1 heterodimer are the 154 kDa alpha4 and the 130 kDa beta7. Most mature lymphocytes, a subset of bone marrow cells, and some of the thymic cells express the alpha4beta7 integrin heterodimer. alpha4beta7 enhances the transendothelial migration of lymphocytes, and interacts with several ligands (fibronectin, CD106, and MAdCAM-1). The interaction of DATK32 with the alpha4beta7 induces the alpha4beta7-dependent lymphocyte aggregation and inhibits LPAM-1-dediated cell adhesion.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

77-136

List Size:
0.1 mg

List Price:

$249.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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