LPAM 1 (Integrin a4, CD49d) Antibody

CATALOG NUMBER: 79-719

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
LPAM-1 (Integrin a4, CD49d) antibody was raised against a peptide sequence around aa.1024~1028 (Y-I-N-S-K) derived from Human LPAM-1 (Integrin α4, CD49d).
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of total LPAM-1(Integrin α4, CD49d) protein.
Predicted Molecular Weight:
70, 140, 180 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
ITGA4
Additional Names:
IA4, CD49D, CTNNB, OK/SW-cl.35, PRO2286, IA4, MGC90518, ITGA4
Protein Accession Number:
NP_000876.3
Protein Gi Number:
67191027
Ncbi Gene Id Number:
3676
Background:
Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
Background Reference 1:
Iida J., Meijne A. M. L., Oegema T. R. Jr., Yednock T. A., Kovach N. L., Furcht L. T., McCarthy J. B. J. Biol. Chem. 273:5955-5962 (1998) Liu S., Thomas S. M., Woodside D. G., Rose D. M., Kiosses W. B., Pfaff M., Ginsberg M. H. Nature 402:676-681 (1999)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-719

List Size:
0.1 mg

List Price:

$370.00

Shipping Info
Customize your order
Custom Antibody Services

New & Featured Products

CATALOG NUMBER: PM-7369-HRP

CATALOG NUMBER: PM-7369-biotin

CATALOG NUMBER: PM-7369