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Western blot analysis in mouse spleen tissue lysates (35ug/lane).
Western blot analysis in mouse spleen tissue lysates (35ug/lane).

LPHN3 Antibody

CATALOG NUMBER: 59-359

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Immunogen:
This LPHN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-397 amino acids from the N-terminal region of human LPHN3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
162 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LPHN3
Additional Names:
Latrophilin-3, Calcium-independent alpha-latrotoxin receptor 3, CIRL-3, Lectomedin-3, LPHN3, KIAA0768, LEC3
Protein Accession Number:
Q9HAR2
Protein Gi Number:
47116772
Ncbi Gene Id Number:
23284
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the latrophilin subfamily ofG-protein coupled receptors (GPCR). Latrophilins may function inboth cell adhesion and signal transduction. In experiments withnon-human species, endogenous proteolytic cleavage within acysteine-rich GPS (G-protein-coupled-receptor proteolysis site)domain resulted in two subunits (a large extracellular N-terminalcell adhesion subunit and a subunit with substantial similarity tothe secretin/calcitonin family of GPCRs) being non-covalently boundat the cell membrane.
Background Reference 1:
Arcos-Burgos, M., et al. Mol. Psychiatry 15(11):1053-1066(2010)
Background Reference 2:
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Background Reference 3:
Kasperaviciute, D., et al. Brain 133 (PT 7), 2136-2147 (2010) :
Background Reference 4:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-359

List Size:
400 ul

List Price:

$495.00

Datasheet
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