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Western blot analysis in mouse heart tissue lysates (35ug/lane).
Western blot analysis of LPXN using rabbit polyclonal LPXN Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the LPXN gene.
Western blot analysis in mouse heart tissue lysates (35ug/lane).

LPXN Antibody

CATALOG NUMBER: 59-444

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This LPXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-257 amino acids from the Central region of human LPXN.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
43 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LPXN
Additional Names:
Leupaxin, LPXN, LDLP
Protein Accession Number:
O60711
Ncbi Gene Id Number:
9404
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The product encoded by this gene is preferentiallyexpressed in hematopoietic cells and belongs to the paxillinprotein family. Similar to other members of thisfocal-adhesion-associated adaptor-protein family, it has fourleucine-rich LD-motifs in the N-terminus and four LIM domains inthe C-terminus. It may function in cell type-specific signaling byassociating with PYK2, a member of focal adhesion kinase family. Asa substrate for a tyrosine kinase in lymphoid cells, this proteinmay also function in, and be regulated by, tyrosine kinaseactivity. Alternative splicing results in multiple transcriptvariants encoding distinct isoforms.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Tanaka, T., et al. Cancer Sci. 101(2):363-368(2010)
Background Reference 3:
Dai, H.P., et al. Genes Chromosomes Cancer 48(12):1027-1036(2009)
Background Reference 4:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-444

List Size:
400 ul

List Price:

$495.00

Datasheet
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