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Western blot analysis in mouse lung tissue lysates (35ug/lane).
Western blot analysis in mouse lung tissue lysates (35ug/lane).

LRP5 Antibody

CATALOG NUMBER: 57-888

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This LRP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1163-1190 amino acids from the C-terminal region of human LRP5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
179 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LRP5
Additional Names:
Low-density lipoprotein receptor-related protein 5, LRP-5, LRP5, LR3, LRP7
Protein Accession Number:
O75197
Ncbi Gene Id Number:
4041
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a transmembrane low-density lipoproteinreceptor that binds and internalizes ligands in the process ofreceptor-mediated endocytosis. This protein also acts as aco-receptor with Frizzled protein family members for transducingsignals by Wnt proteins and was originally cloned on the basis ofits association with type 1 diabetes mellitus in humans. Thisprotein plays a key role in skeletal homeostasis and many bonedensity related diseases are caused by mutations in this gene.Mutations in this gene also cause familial exudativevitreoretinopathy.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Lee, D.Y., et al. Menopause 17(5):1064-1070(2010)
Background Reference 3:
Liu, J.M., et al. J. Clin. Endocrinol. Metab. 95 (9), E112-E120 (2010) :
Background Reference 4:
Paternoster, L., et al. J. Clin. Endocrinol. Metab. 95(8):3940-3948(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-888

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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