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Western blot analysis in mouse stomach tissue lysates (35ug/lane).
Western blot analysis in mouse stomach tissue lysates (35ug/lane).

LRRC16A Antibody

CATALOG NUMBER: 59-733

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This LRRC16A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1152-1178 amino acids from the C-terminal region of human LRRC16A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
152 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LRRC16A
Additional Names:
Leucine-rich repeat-containing protein 16A, CARMIL homolog, LRRC16A, CARMIL, CARMIL1a, LRRC16
Protein Accession Number:
Q5VZK9
Protein Gi Number:
74762279
Ncbi Gene Id Number:
55604
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
LRRC16A binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Polasek, O., et al. Croat. Med. J. 51(1):32-39(2010)
Background Reference 3:
Gunjaca, G., et al. Croat. Med. J. 51(1):23-31(2010)
Background Reference 4:
van der Harst, P., et al. Hum. Mol. Genet. 19(2):387-395(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-733

List Size:
400 ul

List Price:

$495.00

Datasheet
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