LTBR Antibody

CATALOG NUMBER: 58-208

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This LTBR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human LTBR.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
47 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LTBR
Additional Names:
Tumor necrosis factor receptor superfamily member 3, Lymphotoxin-beta receptor, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor type III, TNF-RIII, TNFR-III, LTBR, D12S370, TNFCR, TNFR3, TNFRSF3
Protein Accession Number:
P36941
Protein Gi Number:
549090
Ncbi Gene Id Number:
4055
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the tumornecrosis factor (TNF) family of receptors. It is expressed on thesurface of most cell types, including cells of epithelial andmyeloid lineages, but not on T and B lymphocytes. The proteinspecifically binds the lymphotoxin membrane form (a complex oflymphotoxin-alpha and lymphtoxin-beta). The encoded protein and itsligand play a role in the development and organization of lymphoidtissue and tranformed cells. Activation of the encoded protein cantrigger apoptosis.
Background Reference 1:
Cheung, T.C., et al. J. Immunol. 185(3):1949-1958(2010)
Background Reference 2:
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Background Reference 3:
Sanjo, H., et al. J. Biol. Chem. 285(22):17148-17155(2010)
Background Reference 4:
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-208

List Size:
400 ul

List Price:

$495.00

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