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Western blot analysis of LYRM1 in human liver tissue lysate with LYRM1 antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of LYRM1 in rat liver tissue with LYRM1 antibody at 5 μg/mL.
Immunofluorescence of LYRM1 in rat liver tissue with LYRM1 antibody at 20 μg/mL.
Western blot analysis of LYRM1 in human liver tissue lysate with LYRM1 antibody at (A) 1 and (B) 2 μg/mL.
Trial Size

LYRM1 Antibody

CATALOG NUMBER: 5659

Clonality:
Polyclonal
Tested Applications:
ELISA, IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
LYRM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human LYRM1.
The immunogen is located within the first 50 amino acids of LYRM1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IF, IHC-P, WB
Application Note:
LYRM1 antibody can be used for detection of LYRM1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 1304 - Human Liver Tissue Lysate
Purification:
LYRM1 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
LYRM1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
LYRM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LYRM1
Additional Names:
LYRM1 Antibody: A211C6.1, LYR motif-containing protein 1
Protein Accession Number:
EAW66844
Protein Gi Number:
119587248
Ncbi Gene Id Number:
57149
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
LYRM1 Antibody: LYRM1 was one of many genes identified through a suppression subtractive hybridization comparing their expression in omental adipose tissue of obese patients compared to non-obese individuals. Further study confirms that both mRNA and protein levels of LYRM1 are higher in obese individuals. LYRM1 is widely expressed, with highest levels occurring in adipose and liver tissues. It is thought that LYRM1 promotes preadipocyte proliferation and can inhibit apoptosis of preadipocytes. Ectopic LYRM1 expression did not significantly affect adipogenesis, suggesting that LYRM1 can influence adipose tissue homeostasis by modulating the size of the preadipocyte pool.
Background Reference 1:
Qiu J, Ni YH, Gong HX, et al. Identification of differentially expressed genes in omental adipose tissues of obese patients by suppression subtractive hybridization. Biochem. Biophys. Res. Comm.2007; 352:469-78.
Background Reference 2:
Qiu J, Gao CL, Zhang M, et al. LYRM1, a novel gene promotes proliferation and inhibits apoptosis of preadipocytes. Eur. J. Endocrinol.2009; 160:177-84.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

5659

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
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$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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