Trial Size

LYRM2 Antibody

CATALOG NUMBER: 5661

Clonality:
Polyclonal
Tested Applications:
ELISA, ICC, IF, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (94%)
Immunogen:
LYRM2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human LYRM2.
The immunogen is located within the last 50 amino acids of LYRM2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, ICC, IF, WB
Application Note:
LYRM2 antibody can be used for detection of LYRM2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 1203 - A549 Cell Lysate
Positive Control 2:
Cat. No. 17-003 - A549 Cell Slide
Purification:
LYRM2 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
LYRM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
LYRM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
LYRM2
Additional Names:
LYRM2 Antibody: DJ122O8.2, LYR motif-containing protein 2
Protein Accession Number:
NP_065199
Protein Gi Number:
10092689
Ncbi Gene Id Number:
57226
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
LYRM2 Antibody: The Lyr motif found in the LYR-motif containing protein family is similar to that found in the sacchromyces cerevisiae protein ISD11, an iron-sulfur protein in the mitochondria that is thought to play a role in iron homeostasis. No known function has been assigned to LYRM2, although LYRM1 is thought to be involved in preadipocyte progression and LYRM3 has been suggested to be a candidate gene for the branchio-oto-renal (BOR) syndrome.
Background Reference 1:
Shi Y, Ghosh MC, Tong WH, et al. Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis. Hum. Mol. Genet.2009; 18:3014-25.
Background Reference 2:
Qiu J, Gao CL, Zhang M, et al. LYRM1, a novel gene promotes proliferation and inhibits apoptosis of preadipocytes. Eur. J. Endocrinol.2009; 160:177-84.
Background Reference 3:
Lin X, Wells DE, Kimberling WJ, et al. Human NDUFB9 gene: genomic organization and a possible candidate gene associated with deafness disorder mapped to chromosome 8q1 Hum. Heredity1999; 49:75-80.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

5661

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

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